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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Sino Biological/Vitronectin Protein, Human, Recombinant (His Tag)/1/10424-H08H
产品编号:10424-H08H
市  场 价:¥0.00
场      地:美国(厂家直采)
产品分类: 蛋白类>多肽>多肽合成>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:待定
品      牌: Sino Biological
公      司:SinoBiological
公司分类:
Sino Biological/Vitronectin Protein, Human, Recombinant (His Tag)/1/10424-H08H
商品介绍

Vitronectin Protein, Human, Recombinant (His Tag): Product Information

Purity
> 90 % as determined by SDS-PAGE.
Endotoxin
< 1.0="" eu="" per="" μg="" protein="" as="" determined="" by="" the="" lal="">
Activity
Measured by the ability of the immobilized protein to support the adhesion of DU145 human prostate carcinoma cells.When cells are added to Vitronectin-coated plates (10 μg/mL and 100 μL/well), approximately >40% cells will adhere specifically after 30 minutes at 37℃.
Protein Construction
A DNA sequence encoding the human VTN (NP_000629.3) (Met1-Leu478) was expressed with a polyhistidine tag at the C-terminus.
Accession#
NP_000629.3
Expressed Host
HEK293 Cells
Species
Human
Predicted N Terminal
Asp 20
Molecule Mass
The recombinant human VTN consists of 470 amino acids and predicts a molecular mass of 53.7 kDa. As a result of glycosylation, it migrates as an approximately 68.1 kDa band in SDS-PAGE under reducing conditions.
Formulation
Lyophilized from sterile PBS, pH 7.4.Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the hard copy of CoA.
Shipping
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Stability & Storage
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution
A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.

Vitronectin Protein, Human, Recombinant (His Tag): Images

Human Vitronectin/VTN Protein 8800

Vitronectin Protein, Human, Recombinant (His Tag): Synonyms

V75 Protein, Human; Vitronectin Protein, Human; VN Protein, Human; VNT Protein, Human

Vitronectin Background Information

Vitronectin, also known as VTN, is a member of the pexin family. It is an abundant glycoprotein found in serum the extracellular matrix and promotes cell adhesion and spreading. Vitronectin is a secreted protein and exists in either a single chain form or a cleaved, two chain form held together by a disulfide bond. Vitronectin is a plasma glycoprotein implicated as a regulator of diverse physiological process, including blood coagulation, fibrinolysis, pericellular proteolysis, complement dependent immune responses, and cell attachment and spreading. Because of its ability to bind platelet glycoproteins and mediate platelet adhesion and aggregation at sites of vascular injury, vitronectin has become an important mediator in the pathogenesis of coronary atherosclerosis. As a multifunctional protein with a multiple binding domain, Vitronectin interacts with a variety of plasma and cell proteins. Vitronectin binds multiple ligands, including the soluble vitronectin receptor. It may be an independent predictor of adverse cardiovascular outcomes following acute stenting. Accordingly, Vitronectin is suggested to be involved in hemostasis, cell migration, as well as tumor malignancy.
Full Name
vitronectin
References
  • Ekmeki OB, et al. (2006) Vitronectin in atherosclerotic disease. Clin Chim Acta. 368(1-2): 77-83.
  • Derer W, et al. (2009) Vitronectin concentrations predict risk in patients undergoing coronary stenting. Circ Cardiovasc Interv. 2(1): 14-9.
  • Heyman L, et al. (2010) Mesothelial vitronectin stimulates migration of ovarian cancer cells. Cell Biol Int. 34(5): 493-502.

Mouse Vitronectin Proteins

  • Vitronectin Protein, Mouse, Recombinant (His Tag)50585-M08H
  • A Protein Corona Adsorbed to a Bacterial Magnetosome Affects Its Cellular Uptake
    Author
    Lai, W;Li, D;Wang, Q;Nan, X;Xiang, Z;Ma, Y;Liu, Y;Chen, J;Tian, J;Fang, Q;
    Year
    2020
    Journal
    Int J Nanomedicine
    Application
    Circular Dichroism
    PubMed ID: 32189964FoldedExpand

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Stable cell line development service (CHO / HEK293)

品牌介绍

中国生物科技股份有限公司是全球最大的cDNA、重组蛋白和抗体生产商之一。在流感病毒和其他致病性病毒的研究和开发方面,华生物正在迅速领先世界。中生生物所有试剂产品均由公司生产和质量控制,质量保证优于世界其他试剂供应商。它提供了不同菌株的各种抗体、蛋白质和cDNA克隆。临床前动物试验中使用了100多种抗体,抗体产品的检测灵敏度是国际主流试剂供应商的2-10倍

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