商品介绍
TNFRSF1A Matched ELISA Antibody Pair Set,Mouse General Information
Product name
TNFRSF1A Matched ELISA Antibody Pair Set,Mouse
Assay type
Solid Phase Sandwich ELISA
Specificity
Quantitative determination of Mouse TNFRSF1A
Assay range
4.69-300 pg/mL
Materials provided
1. Capture Antibody 0.3 mg/mL of rabbit anti-Mouse TNFRSF1A monoclonal antibody (in PBS, pH 7.4). Dilute to a working concentration of 2 μg/mL in PBS before coating. (Catalog: # 50496-R104)2. Detection Antibody 0.2 mg/mL of rabbit anti-Mouse TNFRSF1A monoclonal antibody conjugated to horseradish-peroxidase (HRP) (in PBS, 50 % HRP-Protector, pH 7.4, store at 4℃). Dilute to working concentration of 0.5 μg/mL in detection antibody dilution buffer before use. (Catalog: # 50496-R028)3. Standard Each vial contains 21 ng of recombinant Mouse TNFRSF1A. Reconstitute with 1 mL detection antibody dilution buffer. After reconstitution, store at -20℃ to -80℃ in a manual defrost freezer. A seven-point standard curve using 2-fold serial dilutions in sample dilution buffer, and a high standard of 300 pg/mL is recommended.
Product overview
This TNFRSF1A Matched ELISA Antibody Pair Set,Mouse is a solid phase sandwich ELISA for quantitative determination of Mouse TNFRSF1A . It contains Mouse TNFRSF1A capture antibody, Mouse TNFRSF1A detector antibody (HRP)and a highly purifiedHEK293-expressedrecombinant Mouse TNFRSF1A protein. This Pair Set is at affordable price for researchers.
Shipping
This Matched ELISA Antibody Pair Set is shipped at ambient temperature.
Storage
Capture Antibody: Aliquot and store at -20℃ to -80℃ for up to 6 months from date of receipt. Avoid repeated freeze-thaw cycles.Detection Antibody: Store at 4℃ and protect it from prolonged exposure to light for up to 6 months from date of receipt. DO NOT FREEZE!Standard: Store lyophilized standard at -20℃ to -80℃ for up to 6 months from date of receipt. Aliquot and store the reconstituted Standard at -80℃ for up to 1 month. Avoid repeated freeze-thaw cycles.
TNFRSF1A Matched ELISA Antibody Pair Set,Mouse Images
TNFRSF1A Matched ELISA Antibody Pair Set,Mouse: Synonyms
CD120a Matched ELISA Antibody Pair Set, Mouse; FPF Matched ELISA Antibody Pair Set, Mouse; p55 Matched ELISA Antibody Pair Set, Mouse; p55-R Matched ELISA Antibody Pair Set, Mouse; TNF-alphaR1 Matched ELISA Antibody Pair Set, Mouse; TNF-R Matched ELISA Antibody Pair Set, Mouse; TNF-R-I Matched ELISA Antibody Pair Set, Mouse; TNF-R1 Matched ELISA Antibody Pair Set, Mouse; TNF-R55 Matched ELISA Antibody Pair Set, Mouse; TNFalpha-R1 Matched ELISA Antibody Pair Set, Mouse; TNFAR Matched ELISA Antibody Pair Set, Mouse; Tnfr-2 Matched ELISA Antibody Pair Set, Mouse; Tnfr1 Matched ELISA Antibody Pair Set, Mouse; TNFR60 Matched ELISA Antibody Pair Set, Mouse; TNFRI Matched ELISA Antibody Pair Set, Mouse; TNFRp55 Matched ELISA Antibody Pair Set, Mouse
TNFRSF1A Background Information
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD120a (cluste of differentiation 120a), also known as TNFR1 / TNFRSF1A, is a member of CD family, tumor necrosis factor receptor superfamily. CD120a is one of the most primary receptors for the tumor necrosis factor-alpha. It has been shown to be localized to both plasma membrane lipid rafts and the trans golgi complex with the help of the death domain (DD). CD120a can activate the transcription factor NF-κB, mediate apoptosis, and regulate inflammation processes.
Full Name
tumor necrosis factor receptor superfamily member 1A
Research Areas
- Neuroinflammation
Related Pathways
Death Receptor Signaling
NF-kB (NFkB) Pathway
TNF Signaling
References
- Zola H, et al. (2007) CD molecules 2006-human cell differentiation molecules. J Immunol Methods. 318 (1-2): 1-5.
- Ho IC, et al. (2009) GATA3 and the T-cell lineage: essential functions before and after T-helper-2-cell differentiation. Nat Rev Immunol. 9 (2): 125-35.
- Matesanz-Isabel J, et al. (2011) New B-cell CD molecules. Immunology Letters.134 (2): 104-12.
- Cottin V, et al. (2002) Restricted localization of the TNF receptor CD120a to lipid rafts: a novel role for the death domain. The journal of immunology. 168: 4095-102.
- Hydroxy-Safflower Yellow A inhibits the TNFR1-Mediated Classical NF-κB Pathway by Inducing Shedding of TNFR1AuthorWang, H;Liu, J;Yang, Y;Cao, Q;Huo, X;Ma, S;Hu, J;Pavalko, FM;Liu, Q;Year2016JournalPhytother ResApplicationELISAFoldedExpand
- ADAM17 Participates in the Protective Effect of Paeoniflorin on Mouse Brain Microvascular Endothelial CellsAuthorWang, H;Ma, S;Li, J;Zhao, M;Huo, X;Sun, J;Sun, L;Hu, J;Liu, Q;Year2017JournalJ. Cell. Physiol.ApplicationELISAPubMed ID: 29215702FoldedExpand
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