商品介绍
SLPI cDNA ORF Clone, Human, C-GFPSpark® tag: General Information
Gene
Species
Human
NCBI Ref Seq
NM_003064.2
RefSeq ORF Size
1128 bp
Sequence Description
Identical with the Gene Bank Ref. ID sequence.
Description
Full length Clone DNA of Human secretory leukocyte peptidase inhibitor with C terminal GFPSpark tag.
Plasmid
Promoter
Enhanced CMV promoter
Vector
pCMV3-C-GFPSpark®
Restriction Sites
KpnI + XbaI(6kb+1.13kb)
Tag Sequence
GFPSpark: GTGAGCAAGGGC……GAGCTGTACAAG
Sequencing Primers
T7( 5" TAATACGACTCACTATAGGG 3" )BGH( 5" TAGAAGGCACAGTCGAGG 3" )
Quality Control
The plasmid is confirmed by full-length sequencing.
Screening
Antibiotic in E.coli
Kanamycin
Antibiotic in Mammalian cell
Hygromycin
Application
Stable or Transient mammalian expression
Storage & Shipping
Shipping
Each tube contains lyophilized plasmid.
Storage
The lyophilized plasmid can be stored at ambient temperature for three months.
SLPI cDNA ORF Neucleotide Sequence and Amino Acid Sequence Information
**Sino Biological guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories.**
SLPI cDNA ORF Clone, Human, C-GFPSpark® tag: Validated Images
SLPI cDNA ORF Clone, Human, C-GFPSpark® tag: Synonyms
ALK1 cDNA ORF Clone, Human; ALP cDNA ORF Clone, Human; BLPI cDNA ORF Clone, Human; HUSI cDNA ORF Clone, Human; HUSI-I cDNA ORF Clone, Human; MPI cDNA ORF Clone, Human; WAP4 cDNA ORF Clone, Human; WFDC4 cDNA ORF Clone, Human
SLPI Background Information
Secretory leukoprotease inhibitor (SLPI), also called antileukoprotease (ALP), is a 12-kDa, nonglycosylated serine protease inhibitor present in mucous secretions. It is thought to play a role in protecting the mucosae from injury associated with inflammation. SLPI is locally produced by serous cells, including bronchial submucosal glands. Elafin and SLPI are members of larger families of proteins secreted predominantly at mucosal sites, and have been shown to be modulated in multiple pathological conditions. Elafin and SLPI are structurally related in that both have a fold with a four-disulfide core or whey acidic protein (WAP) domain responsible for inhibiting proteases. SLPI is a prominent innate immune protein of the respiratory tract, possessing serine protease inhibitor activity, antibacterial activity, and anti-inflammatory/immunomodulatory activity.
Full Name
secretory leukocyte peptidase inhibitor
Research Areas
- Serine Proteases and Regulators
References
- Moreau T, et al. (2008) Multifaceted roles of human elafin and secretory leukocyte proteinase inhibitor (SLPI), two serine protease inhibitors of the chelonianin family. Biochimie. 90(2): 284-95.
- Weldon S, et al. (2007) Innate host defense functions of secretory leucoprotease inhibitor. Exp Lung Res. 33(10): 485-91.
- Williams SE, et al. (2006) SLPI and elafin: one glove, many fingers. Clin Sci (Lond). 110(1): 21-35.
- Kikuchi T, et al. (1996) Regulation of secretory leukoprotease inhibitor gene expression. Nihon Rinsho. 54(2): 405-10.
SLPI cDNA ORF Clone, Human,Related Products
- SLPI cDNA ORF Clone, Human, untaggedHG10343-UT
- SLPI cDNA ORF Clone, Human, C-OFPSpark® tagHG10343-ACR
- SLPI cDNA ORF Clone, Human, C-Myc tagHG10343-CM
- SLPI cDNA ORF Clone, Human, N-Myc tagHG10343-NM
- SLPI cDNA ORF Clone in Cloning Vector, HumanHG10343-M
- SLPI cDNA ORF Clone, Human, C-HA tagHG10343-CY
- SLPI cDNA ORF Clone, Human, N-His tagHG10343-NH
- SLPI cDNA ORF Clone, Human, C-DYKDDDDK (Flag®) tagHG10343-CF
- SLPI cDNA ORF Clone, Human, C-His tagHG10343-CH
- SLPI cDNA ORF Clone, Human, N-HA tagHG10343-NY
- SLPI Lentiviral cDNA ORF Clone, Human, C-GFPSpark® tagHG10343-ACGLN
- SLPI cDNA ORF Clone, Human, N-DYKDDDDK (Flag®) tagHG10343-NF
- Human SLPI qPCR Primer PairHP100381
- Endothelial-Cell-Derived Human Secretory Leukocyte Protease Inhibitor (SLPI) Protects Cardiomyocytes against Ischemia/Reperfusion InjuryAuthorKongpol, K;Nernpermpisooth, N;Prompunt, E;Kumphune, S;Year2019JournalBiomoleculesApplicationexpressionPubMed ID: 31683729FoldedExpand
If you couldn"t find the specific citation, you can:
- Find All Citations
- Submit a CitationGet a Publication Reward
- Leave Us a Message
品牌介绍
中国生物科技股份有限公司是全球最大的cDNA、重组蛋白和抗体生产商之一。在流感病毒和其他致病性病毒的研究和开发方面，华生物正在迅速领先世界。中生生物所有试剂产品均由公司生产和质量控制，质量保证优于世界其他试剂供应商。它提供了不同菌株的各种抗体、蛋白质和cDNA克隆。临床前动物试验中使用了100多种抗体，抗体产品的检测灵敏度是国际主流试剂供应商的2-10倍
公司介绍
销售排行
问答列表
厂家直采
全球直采 正品优价
正品保障
厂家直发 有线跟踪
正规清关
CIF100%正规报关，提供发票
及时交付
限时必达 不达必赔
总部地址：
江苏省苏州市工业园区星湖街218号 苏州生物医药产业园一期（生物纳米园）A4-216(邮编：215125)
工作时间：周一至周五9:00~18:00
技术支持：
短信：18915418616
服务热线：
4000-520-616（全国）
☏ 0512-67156496（苏州）
版权信息：
© 2015- 苏州蚂蚁淘生物科技有限公司 版权所有 中国
友情链接：
联系QQ:764052152
免责声明：
本站有部分内容来自互联网，如无意中侵犯了某个媒体 、公司 、企业或个人等的知识产权，请来电或致函告之，
本网站将在规定时间内给予删除等相关处理。
本网站将在规定时间内给予删除等相关处理。
扫描二维码关注官方微信
获取最新促销及产品信息